C7 Antibody (Monoclonal)

A murine monoclonal antibody to an epitope on C7 protein.

Product Specifications

Citations 4
Clonality

Monoclonal
Immunogen Purified human protein.
Applications See citations and technical data sheet for application info.
Concentration 1.0-1.2 mg/mL
Conjugate Unconjugated
Cross Reactivity

Human, Bovine, Cat, Dog, Hamster, Horse, Rabbit, Rat.
Technical Documents

Ordering Information

For Research Use Only in the United States. Not for use in diagnostic procedures.
Catalog Number A221
Catalog Number (CE) N/A
Size 100 µl
Price (USD) $365.00
Price (EURO) 330,00 €
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Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

A murine monoclonal antibody to an epitope on C7 protein.
Size 100 µl
Concentration

1.0-1.2 mg/mL

Applications See citations and technical data sheet for application info.
Form Liquid. Borate Buffered Saline (pH 8.4 ± 0.2), with ≤ 0.1% Sodium Azide.
Clonality Monoclonal
Immunogen Purified human protein.
Conjugate Unconjugated
Cross Reactivity Human, Bovine, Cat, Dog, Hamster, Horse, Rabbit, Rat.
Isotype IgG1k
Purity ≥ 95% by SDS PAGE
Source

Mouse
Specificity This monoclonal antibody was raised against purified human C7. It is specific for an Antigen expressed on native C7 but not expressed in MAC. It will inhibit the lysis of EA and will not detect membrane bound MAC.
Storage

Short term (30 days) 4˚C. Long term at or below –20˚C.
Background

Complement component C7 is a single-chain glycoprotein with a molecular weight of 95 kD. C7 protein is present in human plasma at an approximate concentration of 55 μg/ml. Upon activation of the lectin, classical or alternative pathways, C7 becomes integrated into the terminal complement complex. The Terminal Complement Complex (TCC) is a general term for both membrane-bound C5b-9, or Membrane Attack Complex (MAC), and fluid phase SC5b-9. TCC is an excellent marker for quantifying the extent of terminal pathway activation in vivo or in vitro. TCC can be deposited on the surface of transformed cells, biomaterials, as well as, a variety of other materials.

Certificate of Analysis

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