The Lyra Direct HSV 1+2/VZV assay is a multiplex in vitro test that detects and differentiates Herpes simplex virus type 1, Herpes simplex virus type 2, and Varicella-zoster virus nucleic acids isolated and purified from cutaneous or mucocutaneous swab specimens obtained from symptomatic patients.
A multiplex real-time PCR reaction is carried out under optimized conditions in a single tube generating amplicons for HSV-1, HSV-2, VZV and the Process Control (PRC). Identification of HSV-1, HSV-2, VZV and the PRC occurs by the use of target-specific primers and fluorescent-labeled probes that hybridize to conserved regions in the genomes of HSV-1, HSV-2, VZV and the PRC.
The Lyra Direct HSV 1+2/VZV assay has one-step reagent set-up and a three-step sample prep. Test results are available in less than 70 minutes. The Lyra Direct HSV 1+2/VZV Assay is available for use on Applied Biosystems® 7500 Fast Dx, QuantStudio™ Dx Real-Time PCR Instrument, and Cepheid® SmartCycler® II.
The Lyra Direct HSV 1+2/VZV assay is one in a growing menu of PCR tests and is used as an aid in the differential diagnosis of Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) and Varicella-zoster virus (VZV) also known as Human herpes virus 3. VZV is the causative agent for chicken pox and shingles.
Please see chart below for ordering information.
The Lyra Direct HSV 1+2/VZV assay is a multiplex in vitro test that detects and differentiates Herpes simplex virus type 1, Herpes simplex virus type 2, and Varicella-zoster virus nucleic acids isolated and purified from cutaneous or mucocutaneous swab specimens obtained from symptomatic patients.
A multiplex real-time PCR reaction is carried out under optimized conditions in a single tube generating amplicons for HSV-1, HSV-2, VZV and the Process Control (PRC). Identification of HSV-1, HSV-2, VZV and the PRC occurs by the use of target-specific primers and fluorescent-labeled probes that hybridize to conserved regions in the genomes of HSV-1, HSV-2, VZV and the PRC.
The Lyra Direct HSV 1+2/VZV assay has one-step reagent set-up and a three-step sample prep. Test results are available in less than 70 minutes. The Lyra Direct HSV 1+2/VZV Assay is available for use on Applied Biosystems® 7500 Fast Dx, QuantStudio™ Dx Real-Time PCR Instrument, and Cepheid® SmartCycler® II.
The Lyra Direct HSV 1+2/VZV assay is one in a growing menu of PCR tests and is used as an aid in the differential diagnosis of Herpes simplex virus 1 and 2 (HSV-1 and HSV-2) and Varicella-zoster virus (VZV) also known as Human herpes virus 3. VZV is the causative agent for chicken pox and shingles.
Please see chart below for ordering information.
| Ordering information | ||
| Catalog number | Description | Kit size / Case size |
| M102 | Assay Kit | 96 tests |
| M121 | Quidel Molecular HSV 1+2/VZV Control Set | 10 reactions |
Features & benefits
Rehydration solution is simply added to the lyophilized Master Mix for one-step reagent set-up.
Speedy results in less than 75 minutes after extraction.
Simplified and uniform workflow with standard pipetting volumes for easy training.
To access safety data sheets, package inserts, quick reference guides and all other technical and promotional materials, visit our technical documents library.
- Specifications
| Product specifications | |
| Sample type | Cutaneous or mucocutaneous swab specimens |
| Time to results | Less than 60 minutes |
| Reagent storage conditions | 2°C to 8°C |
| Controls storage conditions | 2°C to 8°C |
| Sample volume needed for extraction | 100 µL |
| Purified nucleic acid volume needed to testing | 5 µL |
| Sensitivity* | Cutaneous: HSV-1 100.0%, HSV-2 97.1%, VZV 96.3%; Mucocutaneous: HSV-1 95.1%, HSV-2 97.9%, VZV 100.0% |
| Specificity* | Cutaneous: HSV-1 98.8%, HSV-2 96.7%, VZV 96.4%; Mucocutaneous: HSV-1 98.2%, HSV-2 97.1%, VZV 99.3% |
| Shelf life | 24 months |
*Data for Applied Biosystems™ 7500 Fast Dx. Refer to Package Insert for additional performance claims.
Related products
- View all
- By disease and condition
