MicroVue™ Mouse/Rat FGF-23 ELISA (Intact)

The MicroVue Mouse FGF-23 (Intact) ELISA Kit is for the measurement of intact FGF-23 in plasma, serum, or cell culture media.


Product Specifications

Citations 9
Specimen

Plasma, Serum, or Cell Culture Supernatent 40 µL

LLOQ 0.006 ng/mL
ULOQ N/A
Assay Time 3.5 hours
Cross Reactivity

None

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number 60-6800
Catalog Number (CE)  
Size 96 wells/test
Price (USD) $870.00
Price (EURO) 775,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

The MicroVue Mouse FGF-23 (Intact) ELISA Kit is for the measurement of intact FGF-23 in plasma, serum, or cell culture media.

Size 96 wells/test
Form

96 well plate with 12 eight-well strips in a resealable foil pouch

Specimen Plasma, Serum, or Cell Culture Supernatent 40 µL
Limit of Detection (LOD) 0.006 ng/mL
Lower Limit of Quantitation (LLOQ) 0.006 ng/mL
Upper Limit of Quantitation (ULOQ) N/A
Intra Assay 2.3 - 4.4%
Inter Assay 4.0%
Standards 6
Controls 2
Sample Values

N/A

Assay Time 3.5 hours
Cross Reactivity

None

Storage

Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components

Background

Fibroblast growth factor 23 (FGF-23), which is produced by bone cells, is a novel member of a large family of related proteins. Its gene encodes a 251 amino acid protein. The amino-terminal portion of FGF-23 (aa 1-24) is hydrophobic and is likely to serve as a signal peptide allowing its secretion into the blood circulation. Its carboxyl-terminal portion (aa 180-251) shares only limited amino acid homology with other members of the FGF family of proteins.

Citations

Title Year Applications Sample Species Sample Sample Details

Phosphate Restriction Prevents Metabolic Acidosis and Curbs Rise in FGF23 and Mortality in Murine Folic Acid-Induced AKI

2024

ELISA

Mouse

Plasma

Murine-Folic Acid-Induced Acute Kidney Injury

Organic phosphate but not inorganic phosphate regulates Fgf23 expression through MAPK and TGF-ꞵ signaling

2024

ELISA

Cell Culture

MC3T3-E1 Cells

The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction

2017

ELISA

Mouse

Plasma

1,25-Dihydroxyvitamin D Maintains Brush Border Membrane NaPi2a and Attenuates Phosphaturia in Hyp Mice

2019

ELISA

Mouse

Serum

1,25-Dihydroxyvitamin D Maintains Brush Border Membrane NaPi2a and Attenuates Phosphaturia in Hyp Mice

2019

ELISA

Mouse

Urine

A G Protein-Coupled, IP3/protein Kinase C Pathway Controlling the Synthesis of Phosphaturic Hormone FGF23.

2019

ELISA

Mouse

Serum

Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice.

2019

ELISA

Mouse

Plasma

Human Heterozygous ENPP1 Deficiency Is Associated With Early Onset Osteoporosis, a Phenotype Recapitulated in a Mouse Model of Enpp1 Deficiency.

2019

ELISA

Mouse

Plasma

Comprehensive Expression Analysis of Cardiac Fibroblast Growth Factor 23 in Health and Pressure-induced Cardiac Hypertrophy.

2024

ELISA

Mouse

Plasma

Pressure-induced Cardiac Hypertrophy

Phosphate Restriction Prevents Metabolic Acidosis and Curbs Rise in FGF23 and Mortality in Murine Folic Acid–Induced AKI

2024

ELISA

Mouse

Plasma

Murine-Folic Acid-Induced Acute Kidney Injury

Selective pharmacological inhibition of the sodium-dependent phosphate co-transporter NPT2a promotes phosphate excretion.

2020

ELISA

Rat

Plasma