Factor H Depleted Sera
Normal human serum depleted of complement Factor H protein.
Product Specifications
| Citations | 0 |
|---|---|
| Description |
Normal human serum depleted of complement Factor H protein. |
| Storage | Store at -70°C or below. Minimize freeze/thaw cycles. |
| Form |
Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | >50 mg protein/mL (refer to CoA for lot specific concentration). |
| Applications |
See citations and technical data sheet for application info. |
Ordering Information
| Catalog Number | A523 |
|---|---|
| Catalog Number (CE) | N/A |
| Size | 1.0 mL |
| Price (USD) | $290.00 |
| Price (EURO) | 255,00 € |
Contact us
| US Phone | +1 (858) 552 1100 |
|---|---|
| EU Phone | +353 (91) 412 474 |
| US Email | contact-us@quidelortho.com |
| EU Email | contact-emea@quidelortho.com |
- Specifications
- Citations
- Certificate of Analysis
Specifications
| Description |
Normal human serum depleted of complement Factor H protein. |
|---|---|
| Size | 1.0 mL |
| Storage |
Store at -70°C or below. Minimize freeze/thaw cycles. |
| Form | Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | >50 mg protein/mL (refer to CoA for lot specific concentration). |
| Applications | See citations and technical data sheet for application info. |
| Purity | No Factor H detectable by immunodiffusion. |
| Source |
Normal human serum |
| Activity | >80% versus normal human serum standard. |
| Molecular Weight | N/A |
| Background |
Normal human serum was depleted of factor H by immunoaffinity chromatography. The product is tested for the absence of factor H by double immunodiffusion. Factor H is a regulator of complement activation. As a result, factor H-Dpl is still capable of activating the alternative pathway and does so spontaneously and very rapidly in the absence of factor H. In fact, activation occurs in less than 2 min in the fluid phase without an activating particle resulting in the consumption of both C3 and factor B. For this reason this depleted serum is stored with 0.1 mM EDTA to inhibit spontaneous activation. |
Citations
| Title | Year | Applications | Sample Species | Sample | Sample Details |
|---|
Certificate of Analysis
