C9 Depleted Sera
Normal human serum depleted of complement C9 protein.
Product Specifications
| Citations | 2 |
|---|---|
| Description |
Normal human serum depleted of complement C9 protein. |
| Storage | Store at -70°C or below. Minimize freeze/thaw cycles. |
| Form |
Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | >50 mg protein/mL (refer to CoA for lot specific concentration). |
| Applications |
See citations and technical data sheet for application info. |
Ordering Information
| Catalog Number | A505 |
|---|---|
| Catalog Number (CE) | N/A |
| Size | 1.0 mL |
| Price (USD) | $195.00 |
| Price (EURO) | 175,00 € |
Contact us
| US Phone | +1 (858) 552 1100 |
|---|---|
| EU Phone | +353 (91) 412 474 |
| US Email | contact-us@quidelortho.com |
| EU Email | contact-emea@quidelortho.com |
- Specifications
- Citations
- Certificate of Analysis
Specifications
| Description |
Normal human serum depleted of complement C9 protein. |
|---|---|
| Size | 1.0 mL |
| Storage |
Store at -70°C or below. Minimize freeze/thaw cycles. |
| Form | Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | >50 mg protein/mL (refer to CoA for lot specific concentration). |
| Applications | See citations and technical data sheet for application info. |
| Purity | No C9 detectable by immunodiffusion. |
| Source |
Normal human serum |
| Activity | >80% versus normal human serum standard. |
| Molecular Weight | N/A |
| Background |
Normal human serum depleted of complement C9 protein by immunoaffinity chromatography. The product is tested for the absence of C9 by functional assays for classical pathway activity and alternative pathway activity and for C9 protein by double immunodiffusion. Note that the C5b678 complex has considerable hemolytic potential without C9 and therefore C9-Dpl is capable of lysing EA and most other cells directly without added C9 if activation is strong enough and if the concentration of depleted serum used is high enough. |
Citations
| Title | Year | Applications | Sample Species | Sample | Sample Details |
|---|---|---|---|---|---|
|
Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells |
2009 | WB |
Cell Culture |
DU-145 Cells |
|
| 2024 | Complement Activation Assay |
Human |
Red Blood Cells |
PNH |
Certificate of Analysis
