Rabbit YKL-40 antibody

A rabbit polyclonal antibody specific to human YKL-40.


Product Specifications

Citations 0
Clonality

Polyclonal

Immunogen Recombinant human YKL-40
Applications See citations and technical data sheet for application info.
Concentration ≥1 mg/mL
Conjugate Unconjugated
Cross Reactivity

Cynomolgus monkey and rhesus macaque

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number 4815
Catalog Number (CE) N/A
Size 100 µl
Price (USD) $385.00
Price (EURO) 340,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

A rabbit polyclonal antibody specific to human YKL-40.

Size 100 µl
Concentration

≥1 mg/mL

Applications See citations and technical data sheet for application info.
Form Liquid. 50 mM Phosphate Buffered Saline
Clonality Polyclonal
Immunogen Recombinant human YKL-40
Conjugate Unconjugated
Cross Reactivity Cynomolgus monkey and rhesus macaque
Isotype Rabbit IgG
Purity >85% by SDS PAGE
Source

Rabbit

Specificity This antibody was tested by various immunoassays to be specific to human YKL-40.
Storage

Short term (30 days) 4°C. Long term at –70°C.

Background

YKL-40, a member of the mammalian chitinase like protein class, is a 40 kD heparin binding glycoprotein. It shares amino acid sequence homology to non-mammalian chitinases but demonstrates no chitinase activity. The name YKL-40 is derived from the protein’s molecular weight and three N-terminus amino acids (tyrosine, lysine and leucine). The biological function of YKL-40 remains largely unknown and is a field of extensive scientific debate. YKL-40 has been shown to be a potent growth factor for connective tissue cells and a potent migration factor for endothelial cells. Several research studies have demonstrated substantial levels of YKL-40 in environments with inflammation or where substantial remodeling of the extracellular matrix (ECM) occurs, including various cancers, active rheumatoid arthritis, inflammatory bowel diseases, severe bacterial infections, and liver fibrosis.