C5 Protein

Purified human C5 protein


Product Specifications

Citations 9
Description

Purified human C5 protein

Storage Store at -70°C or below. Avoid freeze/thaw.
Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.2. No preservative, 0.22 µm filtered.

Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number A403
Catalog Number (CE) N/A
Size 250 µL
Price (USD) $335.00
Price (EURO) 300,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
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Specifications

Description

Purified human C5 protein

Size 250 µL
Storage

Store at -70°C or below. Avoid freeze/thaw.

Form Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.2. No preservative, 0.22 µm filtered.
Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications See citations and technical data sheet for application info.
Purity >95% by SDS-PAGE
Source

Normal human serum

Activity >80% versus normal human serum standard.
Molecular Weight 190,000 Da (2 chains)
Background

Purified human complement component C5. Complement component C5 is unique to the terminal complement pathway. 190 kD C5 protein is comprised of two chains (α 115 kD; ß 75 kD) and is present in plasma at 70 mg/L. Activation of either complement pathway can generate a C5 convertase enzyme capable of cleaving C5 to C5a (a potent anaphylatoxin) and C5b. Together with the other proteins of the terminal pathway, C5b forms the membrane attack complex or MAC.