C1q Protein
Purified human C1q protein
Product Specifications
| Citations | 31 |
|---|---|
| Description |
Purified human C1q protein |
| Storage | Store at -70°C or below. Avoid freeze/thaw. |
| Form |
Frozen liquid. 10 mM HEPES, 300 mM NaCl, pH 7.2, No preservative, 0.22 µm filtered. |
| Concentration | 1.0 mg/mL (refer to CoA for lot specific concentration) |
| Applications |
See citations and technical data sheet for application info. |
Ordering Information
| Catalog Number | A400 |
|---|---|
| Catalog Number (CE) | N/A |
| Size | 1.0 ml |
| Price (USD) | $280.00 |
| Price (EURO) | 250,00 € |
Contact us
| US Phone | +1 (858) 552 1100 |
|---|---|
| EU Phone | +353 (91) 412 474 |
| US Email | contact-us@quidelortho.com |
| EU Email | contact-emea@quidelortho.com |
- Specifications
- Citations
- Certificate of Analysis
Specifications
| Description |
Purified human C1q protein |
|---|---|
| Size | 1.0 ml |
| Storage |
Store at -70°C or below. Avoid freeze/thaw. |
| Form | Frozen liquid. 10 mM HEPES, 300 mM NaCl, pH 7.2, No preservative, 0.22 µm filtered. |
| Concentration | 1.0 mg/mL (refer to CoA for lot specific concentration) |
| Applications | See citations and technical data sheet for application info. |
| Purity | >98% by SDS PAGE |
| Source |
Normal human serum |
| Activity | > 1,000,000 C1H50 units/mg |
| Molecular Weight | 410,000 Da (18 chains) |
| Background |
Purified human complement component C1q. Circulating C1q protein is a hexamer of three unique protein subunits (A, B, and C) with molecular weights of 29, 26 and 22 kD respectively. The assembled hexamer contains a central core or stalk, 6 collagen-like domains and 6 globular protein heads. These globular or terminal regions are responsible for the binding of immunoglobulins (IgM and IgG). As part of the C1 complex (together with two copies each of C1r and C1s) C1q is central to activation of the classical complement pathway. |
