C1q Protein

Purified human C1q protein


Product Specifications

Citations 31
Description

Purified human C1q protein

Storage Store at -70°C or below. Avoid freeze/thaw.
Form

Frozen liquid. 10 mM HEPES, 300 mM NaCl, pH 7.2, No preservative, 0.22 µm filtered.

Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number A400
Catalog Number (CE) N/A
Size 1.0 ml
Price (USD) $280.00
Price (EURO) 250,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

Purified human C1q protein

Size 1.0 ml
Storage

Store at -70°C or below. Avoid freeze/thaw.

Form Frozen liquid. 10 mM HEPES, 300 mM NaCl, pH 7.2, No preservative, 0.22 µm filtered.
Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications See citations and technical data sheet for application info.
Purity >98% by SDS PAGE
Source

Normal human serum

Activity > 1,000,000 C1H50 units/mg
Molecular Weight 410,000 Da (18 chains)
Background

Purified human complement component C1q. Circulating C1q protein is a hexamer of three unique protein subunits (A, B, and C) with molecular weights of 29, 26 and 22 kD respectively. The assembled hexamer contains a central core or stalk, 6 collagen-like domains and 6 globular protein heads. These globular or terminal regions are responsible for the binding of immunoglobulins (IgM and IgG). As part of the C1 complex (together with two copies each of C1r and C1s) C1q is central to activation of the classical complement pathway.