Factor Ba Protein

Purified human Factor Ba protein


Product Specifications

Citations 0
Description

Purified human Factor Ba protein

Storage Store at -70°C or below. Avoid freeze/thaw.
Form

Frozen liquid. Phosphate-buffered saline, pH 7.3. No preservative, 0.22 µm filtered.

Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number A422
Catalog Number (CE) N/A
Size 100 µL
Price (USD) $285.00
Price (EURO) 255,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
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Specifications

Description

Purified human Factor Ba protein

Size 100 µL
Storage

Store at -70°C or below. Avoid freeze/thaw.

Form Frozen liquid. Phosphate-buffered saline, pH 7.3. No preservative, 0.22 µm filtered.
Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications See citations and technical data sheet for application info.
Purity >95% by SDS-PAGE
Source

Normal human serum

Activity No activity
Molecular Weight 33,000 Da (single chain)
Background

Factor Ba is the fragment of complement factor B that results from activation of the alternative pathway. The factor Ba fragment from factor B which was purified from normal human serum. Complement factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. Factor B is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 µg/mL. In the presence of Mg++ factor B binds to C3b and the C3bB complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease. Cleavage of factor B by factor D causes the release of the Ba fragment (33,000 Da) and leaves the 60,000 Da Bb fragment bound to C3b.

Citations

Title Year Applications Sample Species Sample Sample Details