The Solana GAS Assay is a rapid in vitro diagnostic test for the qualitative detection of Group A β-hemolytic Streptococcus (Streptococcus pyogenes) nucleic acids isolated from throat swab specimens obtained from patients with signs and symptoms of pharyngitis, such as sore throat.
The Solana GAS Assay, when performed on the Solana instrument, allows for the rapid, accurate detection of group A strep without the need for culture confirmation.
The assay utilizes helicase-dependent amplification (HDA) of the DNase B (sdaB) sequence and fluorescent probe-based detection in the Solana instrument to determine assay results.
A throat swab sample or an aliquot of liquid transport media is lysed by simple heat treatment, diluted, and added to a Reaction Tube containing the lyophilized HDA reagents including primers specific for the amplification of the DNAase B (sdaB) sequence as well as sequence specific probes. Competitive process control (PRC) is included in the Lysis Tube to monitor sample processing, inhibitory substances in clinical samples, reagent failure or instrument failure.
Results are displayed on the touchscreen, can be saved to the instrument, printed, and are capable of being sent to the LIS and exported through one of Solana’s four USB ports. Solana GAS Assay is supported by the power of the Virena® System.
Assay kit
Catalog number: M301
Kit size/Case size: 48 tests
Quidel Molecular Strep A+G Control Set
Catalog number: M111
Kit size/Case size: 0.5 mL
The Solana GAS Assay is a rapid in vitro diagnostic test for the qualitative detection of Group A β-hemolytic Streptococcus (Streptococcus pyogenes) nucleic acids isolated from throat swab specimens obtained from patients with signs and symptoms of pharyngitis, such as sore throat.
The Solana GAS Assay, when performed on the Solana instrument, allows for the rapid, accurate detection of group A strep without the need for culture confirmation.
The assay utilizes helicase-dependent amplification (HDA) of the DNase B (sdaB) sequence and fluorescent probe-based detection in the Solana instrument to determine assay results.
A throat swab sample or an aliquot of liquid transport media is lysed by simple heat treatment, diluted, and added to a Reaction Tube containing the lyophilized HDA reagents including primers specific for the amplification of the DNAase B (sdaB) sequence as well as sequence specific probes. Competitive process control (PRC) is included in the Lysis Tube to monitor sample processing, inhibitory substances in clinical samples, reagent failure or instrument failure.
Results are displayed on the touchscreen, can be saved to the instrument, printed, and are capable of being sent to the LIS and exported through one of Solana’s four USB ports. Solana GAS Assay is supported by the power of the Virena® System.
Assay kit
Catalog number: M301
Kit size/Case size: 48 tests
Quidel Molecular Strep A+G Control Set
Catalog number: M111
Kit size/Case size: 0.5 mL
Features & benefits
Rapid method of isothermal nucleic acid amplification that does not require thermocycling with RT-HDA technology.
Easy-to-use format, just add processed sample to rehydrate using Lyophilized Master Mix reagent.
Small, easy-to-use instrument eliminates the need for dedicated molecular space and costly capital equipment, allowing for testing in smaller labs.
To access safety data sheets, package inserts, quick reference guides and all other technical and promotional materials, visit our technical documents library.
- Specifications
- Learning hub
| Product specifications | |
| Sample type | Throat swab specimens obtained from patients symptomatic of acute pharyngitis |
| Time to results | Approximately 35 minutes |
| Reagent storage conditions | Lysis, Dilution and Reaction Tubes; 2˚C to 8˚C |
| Controls storage conditions | 2˚C to 8˚C |
| Sample preparation storage conditions (cultured enriched broth) | 25˚C to 2˚C for up to 2 days and then at 2˚C to 8˚C for up to 6 more days before testing or at ≤–15˚C or ≤–70˚C for up to 34 days before testing |
| Clinical Senstivity | 98.2% (95% CI 95.5% to 99.3%) |
| Clinical Specifity | 97.2% (95% CI 95.9% to 98.1%) |
| LOD | 6.81 x 104 CFU/mL |
Solana in action
"The Use of Molecular Diagnostics in the Physician Office Lab"
