MicroVue™ DPD EIA

The MicroVue DPD EIA offers a laboratory test that measures deoxypyridinoline cross-links (Dpd).


Product Specifications

Citations 15
Specimen

Urine 50 μL

LLOQ 3 nmol/L
ULOQ 300 nmol/L
Assay Time 3 hours
Cross Reactivity

Baboon, Cow, Cynomolgous monkey, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, Rhesus monkey, Sheep, Squirrel monkey

Ordering Information

For In Vitro Diagnostic Use.
Catalog Number 8007
Catalog Number (CE)  
Size 96 wells/test
Price (USD) $970.00
Price (EURO) 680,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

The MicroVue DPD EIA offers a laboratory test that measures deoxypyridinoline cross-links (Dpd).

Size 96 wells/test
Form

96 well plate with 12 eight-well strips in a resealable foil pouch

Specimen Urine 50 μL
Limit of Detection (LOD) 1.1 nmol/L
Lower Limit of Quantitation (LLOQ) 3 nmol/L
Upper Limit of Quantitation (ULOQ) 300 nmol/L
Intra Assay 4.3–8.4%
Inter Assay 3.1–4.8%
Standards 6
Controls 2
Sample Values

Females (Ages 25–44) 3.0–7.4 nmol DPD/nmol Creatinine, Males (Ages 25–55) 2.3–5.4 nmol DPD/nmol Creatinine

Assay Time 3 hours
Cross Reactivity

Baboon, Cow, Cynomolgous monkey, Dog, Guinea pig, Horse, Mouse, Pig, Rabbit, Rat, Rhesus monkey, Sheep, Squirrel monkey

Storage

Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components

Background

DPD is a specific marker of bone resorption which is excreted in the urine. MicroVue DPD EIA provides a quantitative measure of deoxypyridinoline (Dpd), a cross-link of bone type 1 collagen released during the resorption process. Dpd is excreted unmetabolized in urine. Elevated levels of urinary Dpd indicate elevated bone resorption in individuals. MicroVue DPD is a urinary assay that provides a quantitative measure of the excretion of deoxypyridinoline (DPD) crosslinks as an indicator of bone resorption. Elevated levels of urinary DPD indicate elevated bone resorption in individuals. Measurement of DPD is intended for use as an aid in monitoring bone resorption changes in postmenopausal women receiving hormonal or bisphosphonate antiresorptive therapies and in individuals diagnosed with osteoporosis.

Citations

Title Year Applications Sample Species Sample Sample Details

Changes in biomarkers of bone resorption over the first six months after pediatric hematopoietic cell transplantation.

2012

ELISA

Human

Urine

Hematopoietic cell transplantation

Age-related bone turnover markers and osteoporotic risk in native Chinese women.

2014

ELISA

Human

Serum

Biomarkers of bone remodeling in children with mucopolysaccharidosis types I, II, and VI.

2014

ELISA

Human

Urine

Mucopolysaccharidosis Types I, II, and VI, children

Systemic transplantation of human adipose-derived stem cells stimulates bone repair by promoting osteoblast and osteoclast function

2011

ELISA

Mouse

Urine

The role of the renal ammonia transporter Rhcg in metabolic responses to dietary protein.

2014

ELISA

Mouse

Urine

Estrogen Regulates Bone Turnover by Targeting RANKL Expression in Bone Lining Cells.

2017

ELISA

Mouse

Urine

The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction

2017

ELISA

Mouse

Urine

Selective inhibition of receptor activator of NF-κB ligand (RANKL) in hematopoietic cells improves outcome after experimental myocardial infarction.

2018

ELISA

Mouse

Urine

Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches.

2018

ELISA

Mouse

Urine

Integrin alpha11 is an Osteolectin receptor and is required for the maintenance of adult skeletal bone mass.

2019

ELISA

Mouse

Urine

Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice.

2019

ELISA

Mouse

Urine

Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis.

2016

ELISA

Rabbit

Urine

Moderately Low Magnesium Intake Impairs Growth of Lean Body Mass in Obese-Prone and Obese-Resistant Rats Fed a High-Energy Diet.

2016

ELISA

Rat

Urine

Dual Therapeutic Action of a Neutralizing Anti-FGF2 Aptamer in Bone Disease and Bone Cancer Pain.

2016

ELISA

Rat

Urine

Bone Protective Effects of Danggui Buxue Tang Alone and in Combination With Tamoxifen or Raloxifene in vivo and in vitro.

2018

ELISA

Rat

Urine