Factor P Depleted Sera

Normal human serum depleted of complement Factor P protein.


Product Specifications

Citations1
Description

Normal human serum depleted of complement Factor P protein.

Storage

Store at -70°C or below. Minimize freeze/thaw cycles.

Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration

>50 mg protein/mL (refer to CoA for lot specific concentration).

Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog NumberA512
Catalog Number (CE)N/A
Size1.0 mL
Price (USD)$225.00
Price (EURO)195,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

Normal human serum depleted of complement Factor P protein.

Size1.0 mL
Storage

Store at -70°C or below. Minimize freeze/thaw cycles.

Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration>50 mg protein/mL (refer to CoA for lot specific concentration).
ApplicationsSee citations and technical data sheet for application info.
PurityNo Factor P detectable by immunodiffusion.
SourceNormal human serum
Activity>80% versus normal human serum standard.
Molecular WeightN/A
Background

Normal human serum was depleted of factor P (properdin) by immunoaffinity chromatography. The product is tested for the absence of factor P by double immunodiffusion. Factor P is a positive regulator of alternative pathway complement activation. As a result, Factor P-Dpl is still capable of activating the alternative pathway but activation is slower than with properdin present.

Citations

TitleYearApplicationsSample SpeciesSampleSample Details

Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans.

2011FCHuman

Serum

N/A