Factor I Protein

Purified human Factor I protein

Store at -70°C or below. Avoid freeze/thaw.

Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.2. No preservative, 0.22 µm filtered.

Purified human complement component Factor I. Factor I is a fluid phase complement regulatory enzyme. It consists of two peptide chains with molecular weights of 50 kD and 38 kD, respectively. Factor I is present in plasma at 35 mg/L. With Factor H, CR1 or C4 Binding Protein acting as a cofactor, Factor I cleaves the C3b subunit of the alternative and classical pathway convertases, thereby inactivating them.