Factor D Protein

Purified human Factor D protein


Product Specifications

Citations2
Description

Purified human Factor D protein

Storage

Store at -70°C or below. Avoid freeze/thaw.

Form

Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration

0.1 mg/mL (refer to CoA for lot specific concentration)

Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog NumberA409
Catalog Number (CE)N/A
Size250 µL
Price (USD)$290.00
Price (EURO)255,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

Purified human Factor D protein

Size250 µL
Storage

Store at -70°C or below. Avoid freeze/thaw.

Form

Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration0.1 mg/mL (refer to CoA for lot specific concentration)
ApplicationsSee citations and technical data sheet for application info.
Purity>95% by SDS-PAGE
SourceNormal human serum
Activity>95% versus normal human serum standard
Molecular Weight24,000 Da (single chain)
Background

Purified human complement Factor D. Factor D is unique to the Alternative Complement Pathway. It consists of a single peptide chain with a molecular weight of 24 kD. Factor D is a specific serine protease which cleaves Factor B complexed with C3b (or hydrolyzed C3) in a single position to yield Bb and Ba.

Citations

TitleYearApplicationsSample SpeciesSampleSample Details

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo.

2017Dot BlotHuman

Serum

SPIO nanoworms

Inhibition of aberrant complement activation by a dimer of acetylsalicylic acid.

2015ELISA, WBHuman

Serum

Acetyl salicylic acid dimer 5,5'-methylenebis(2-acetoxybenzoic acid) (DAS)