C9 Depleted Sera

Normal human serum depleted of complement C9 protein.


Product Specifications

Citations1
Description

Normal human serum depleted of complement C9 protein.

Storage

Store at -70°C or below. Minimize freeze/thaw cycles.

Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration

>50 mg protein/mL (refer to CoA for lot specific concentration).

Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog NumberA505
Catalog Number (CE)N/A
Size1.0 mL
Price (USD)$195.00
Price (EURO)175,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

Normal human serum depleted of complement C9 protein.

Size1.0 mL
Storage

Store at -70°C or below. Minimize freeze/thaw cycles.

Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration>50 mg protein/mL (refer to CoA for lot specific concentration).
ApplicationsSee citations and technical data sheet for application info.
PurityNo C9 detectable by immunodiffusion.
SourceNormal human serum
Activity>80% versus normal human serum standard.
Molecular WeightN/A
Background

Normal human serum depleted of complement C9 protein by immunoaffinity chromatography. The product is tested for the absence of C9 by functional assays for classical pathway activity and alternative pathway activity and for C9 protein by double immunodiffusion. Note that the C5b678 complex has considerable hemolytic potential without C9 and therefore C9-Dpl is capable of lysing EA and most other cells directly without added C9 if activation is strong enough and if the concentration of depleted serum used is high enough.

Citations

TitleYearApplicationsSample SpeciesSampleSample Details

Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells

2009WBCell Culture

DU-145 Cells

N/A