C3a Antibody (Monoclonal)

A murine monoclonal antibody to the human C3a domain of C3.

100 µl

Purified human protein.

IgG1k

≥ 95% by SDS PAGE

This monoclonal antibody was raised against purified human C3. It is specific for an antigen expressed on the C3a domain of C3 and therefore reactive to C3 and C3a.

Short term (30 days) 4˚C. Long term at or below –20˚C.

The human complement component, C3, consists of two disulfide-bonded subunits (Alpha – 115,000 kD and Beta – 75,000 kD). The concentration of C3 in serum is approximately 1.25 + 0.52 mg/ml. Under normal conditions, activation of either the Classical, Lectin or Alternative Complement Pathways produces C3 convertase which cleaves C3 into two fragments – C3a, an anaphylatoxin, and C3b. Quidel’s monoclonal antibodies to complement antigens were prepared using standard techniques. They are purified from mouse ascites fluid via Protein A affinity chromatography. Quidel’s Anti-Human C3a monoclonal antibody was raised against highly pure human C3 protein.