SC5b-9 Protein

Purified human SC5b-9 protein

Product Specifications

Citations 1
Description

Purified human SC5b-9 protein
Storage Store at -70°C or below. Avoid freeze/thaw.
Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.
Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications

See citations and technical data sheet for application info.
Technical Documents

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number A415
Catalog Number (CE) N/A
Size 100 µL
Price (USD) $320.00
Price (EURO) 255,00 €
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Specifications

Description

Purified human SC5b-9 protein
Size 100 µL
Storage

Store at -70°C or below. Avoid freeze/thaw.

Form Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.
Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications See citations and technical data sheet for application info.
Purity >90% by SDS-PAGE
Source

Normal human serum
Activity No activity
Molecular Weight 1,030,000 Da (~13 chains)
Background

Vitronectin (S Protein) binds to membrane attack complexes that fail to insert into membranes. The result is a soluble complex of S Protein and C5b-9 and this has been named SC5b-9. Activation of complement in the absence of bilipid layer membranes results in most of the activated C5 forming SC5b-9 complexes. This can occur with activating particles such as immune complexes, yeast and bacterial cell walls. The SC5b-9 complexes can have more than one C9 (usually three) and more than one S Protein (usually three) per complex.

Certificate of Analysis

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