MicroVue™ Serum PYD
The MicroVue Serum PYD provides a quantitative measure of the excretion of pyridinoline cross-link (Pyd) in serum.
Product Specifications
| Citations | 9 |
|---|---|
| Specimen |
Serum 25 μL |
| LLOQ | N/A |
| ULOQ | N/A |
| Assay Time | 20-26 hours |
| Cross Reactivity |
Baboon, Cat, Cow, Dog, Guinea Pig, Horse, Mouse, Pig, Rat, Rhesus monkey |
Ordering Information
| Catalog Number | 8019 |
|---|---|
| Catalog Number (CE) | |
| Size | 96 wells/test |
| Price (USD) | $970.00 |
| Price (EURO) | 865,00 € |
Contact us
| US Phone | +1 (858) 552 1100 |
|---|---|
| EU Phone | +353 (91) 412 474 |
| US Email | contact-us@quidelortho.com |
| EU Email | contact-emea@quidelortho.com |
- Specifications
- Citations
- Certificate of Analysis
Specifications
| Description |
The MicroVue Serum PYD provides a quantitative measure of the excretion of pyridinoline cross-link (Pyd) in serum. |
|---|---|
| Size | 96 wells/test |
| Form |
96 well plate with 12 eight-well strips in a resealable foil pouch |
| Specimen | Serum 25 μL |
| Limit of Detection (LOD) | 0.4 nmol/L |
| Lower Limit of Quantitation (LLOQ) | N/A |
| Upper Limit of Quantitation (ULOQ) | N/A |
| Intra Assay | 4.8–10.0% |
| Inter Assay | 4.8–9.8% |
| Standards | 1 |
| Controls | 2 |
| Sample Values |
Adult (25–55) 1.09–2.79 nmol/L |
| Assay Time | 20-26 hours |
| Cross Reactivity |
Baboon, Cat, Cow, Dog, Guinea Pig, Horse, Mouse, Pig, Rat, Rhesus monkey |
| Storage |
Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components |
| Background |
Pyridinoline cross-links are an indicator of type I collagen resorption, especially bone collagen. In humans, the total pool of urinary Pyd is approximately 45% free while the remaining fraction is bound to oligopeptides ranging from small linear peptides to very large cross-linked structures in excess of 10,000 Da. The proportion of free to total cross-links appears to be constant in healthy individuals and those with metabolic bone diseases or arthritis conditions, thus providing the rationale for measuring free Pyd. |
Citations
| Title | Year | Applications | Sample Species | Sample | Sample Details |
|---|---|---|---|---|---|
| 2014 | ELISA |
Human |
Serum |
||
| 2016 | ELISA |
Human |
Serum |
||
| 2018 | ELISA |
Human |
Serum |
||
| 2011 | ELISA |
Mouse |
Serum |
||
| 2013 | ELISA |
Mouse |
Serum |
||
| 2020 | ELISA |
Mouse |
Serum |
||
|
Proteomic analysis of altered extracellular matrix turnover in bleomycin-induced pulmonary fibrosis. |
2014 | ELISA |
Mouse |
Lung Tissue |
|
|
Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency. |
2020 | ELISA |
Mouse |
Serum |
|
| 2015 | ELISA |
Rat |
Heart Tissue |
Certificate of Analysis
