Factor P Depleted Sera

Normal human serum depleted of complement Factor P protein.


Product Specifications

Citations 1
Description

Normal human serum depleted of complement Factor P protein.

Storage Store at -70°C or below. Minimize freeze/thaw cycles.
Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration >50 mg protein/mL (refer to CoA for lot specific concentration).
Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number A512
Catalog Number (CE) N/A
Size 1.0 mL
Price (USD) $225.00
Price (EURO) 195,00 €

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EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
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Specifications

Description

Normal human serum depleted of complement Factor P protein.

Size 1.0 mL
Storage

Store at -70°C or below. Minimize freeze/thaw cycles.

Form Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.
Concentration >50 mg protein/mL (refer to CoA for lot specific concentration).
Applications See citations and technical data sheet for application info.
Purity No Factor P detectable by immunodiffusion.
Source

Normal human serum

Activity >80% versus normal human serum standard.
Molecular Weight N/A
Background

Normal human serum was depleted of factor P (properdin) by immunoaffinity chromatography. The product is tested for the absence of factor P by double immunodiffusion. Factor P is a positive regulator of alternative pathway complement activation. As a result, Factor P-Dpl is still capable of activating the alternative pathway but activation is slower than with properdin present.

Citations

Title Year Applications Sample Species Sample Sample Details

Linkage specificity and role of properdin in activation of the alternative complement pathway by fungal glycans.

2011

FC

Human

Serum