C6 Protein

Purified human C6 protein


Product Specifications

Citations 1
Description

Purified human C6 protein

Storage Store at -70°C or below. Avoid freeze/thaw.
Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number A404
Catalog Number (CE) N/A
Size 250 µL
Price (USD) $295.00
Price (EURO) 265,00 €

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EU Phone+353 (91) 412 474
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Specifications

Description

Purified human C6 protein

Size 250 µL
Storage

Store at -70°C or below. Avoid freeze/thaw.

Form Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.
Concentration 1.0 mg/mL (refer to CoA for lot specific concentration)
Applications See citations and technical data sheet for application info.
Purity >90% by SDS-PAGE
Source

Normal human serum

Activity >70% versus normal human serum standard
Molecular Weight 105,000 Da (single chain)
Background

Purified human complement component C6 is unique to the terminal complement pathway. It is a single chain protein with a molecular weight of 120 KDA and is present in plasma at approximately 60 mg/L. Together with the other proteins of the terminal pathway, C6 constitutes the membrane attack complex or MAC.

Citations

Title Year Applications Sample Species Sample Sample Details

Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells

2017

WB

Cell Culture

RPE Cells