C3 Depleted Sera
Normal human serum depleted of complement C3 protein.
Product Specifications
| Citations | 5 |
|---|---|
| Description |
Normal human serum depleted of complement C3 protein. |
| Storage | Store at -70°C or below. Minimize freeze/thaw cycles. |
| Form |
Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | >50 mg protein/mL (refer to CoA for lot specific concentration). |
| Applications |
See citations and technical data sheet for application info. |
Ordering Information
| Catalog Number | A508 |
|---|---|
| Catalog Number (CE) | N/A |
| Size | 1.0 mL |
| Price (USD) | $265.00 |
| Price (EURO) | 235,00 € |
Contact us
| US Phone | +1 (858) 552 1100 |
|---|---|
| EU Phone | +353 (91) 412 474 |
| US Email | contact-us@quidelortho.com |
| EU Email | contact-emea@quidelortho.com |
- Specifications
- Citations
- Certificate of Analysis
Specifications
| Description |
Normal human serum depleted of complement C3 protein. |
|---|---|
| Size | 1.0 mL |
| Storage |
Store at -70°C or below. Minimize freeze/thaw cycles. |
| Form | Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | >50 mg protein/mL (refer to CoA for lot specific concentration). |
| Applications | See citations and technical data sheet for application info. |
| Purity | No C3 detectable by immunodiffusion. |
| Source |
Normal human serum |
| Activity | >80% versus normal human serum standard. |
| Molecular Weight | N/A |
| Background |
C3-Dpl is normal human serum in which C3 has been removed by immunoaffinity chromatography. The product is tested for the absence of C3 activity by classical and alternative pathway functional assays and for C3 protein by double immunodiffusion. |
Citations
| Title | Year | Applications | Sample Species | Sample | Sample Details |
|---|---|---|---|---|---|
| 2009 | Complement Activation Assay |
Cell Culture |
Vero E6 cells |
||
| 2014 | IF |
Cell Culture |
TIME-KSHV cells |
||
|
Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo. |
2017 | Dot Blot |
Human |
Serum |
SPIO nanoworms |
|
Extracellular vesicles from KSHV-infected endothelial cells activate the complement system |
2017 | ELISA |
Human |
HUVEC Cells |
KSHV infection |
|
Functional Analyses of Complement Convertases Using C3 and C5-Depleted Sera |
2012 | Complement Inhibition Assay |
Sheep |
Erythrocytes |
Certificate of Analysis
