C2 Depleted Sera

Normal human serum depleted of complement C2 protein.


Product Specifications

Citations 1
Description

Normal human serum depleted of complement C2 protein.

Storage Store at -70°C or below. Minimize freeze/thaw cycles.
Form

Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration >50 mg protein/mL (refer to CoA for lot specific concentration).
Applications

See citations and technical data sheet for application info.

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number A500
Catalog Number (CE) N/A
Size 1.0 mL
Price (USD) $195.00
Price (EURO) 150,00 €

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Specifications

Description

Normal human serum depleted of complement C2 protein.

Size 1.0 mL
Storage

Store at -70°C or below. Minimize freeze/thaw cycles.

Form Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.
Concentration >50 mg protein/mL (refer to CoA for lot specific concentration).
Applications See citations and technical data sheet for application info.
Purity No C2 detectable by immunodiffusion.
Source

Normal human serum

Activity >80% versus normal human serum standard when reconstituted.
Molecular Weight N/A
Background

Normal human serum depleted of complement C2 protein by immunoaffinity chromatography. The product is tested for the absence of C2 by functional assays for classical pathway activity and for C2 protein by double immunodiffusion. The absence of C2 also prevents complement activation by the lectin pathway but the alternative pathway will still activate on appropriate surfaces.

Citations

Title Year Applications Sample Species Sample Sample Details

Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking.

2021

ELISA

Human

Plasma